Craniofacial dysmorphology 
In its extreme form holoprosencephaly is accompanied by failure of development of eyes and midline facial structures.
As in this example, there may be only a single eye (cyclopia).
Cleft palate is often an associated defect.

Craniofacial dysmorphology

  • In its extreme form holoprosencephaly is accompanied by failure of development of eyes and midline facial structures.
  • As in this example, there may be only a single eye (cyclopia).
  • Cleft palate is often an associated defect.
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