bpod-mrc
bpod-mrc:

14 September 2014
Blood Cleaner
Microbial pathogens in the bloodstream can lead to sepsis, when the immune system goes wild in response to the infection, often causing organ failure and death. It usually takes days to identify the culprit, so doctors use broad-spectrum antibiotics, which are not very effective. Now, though, researchers have debuted a potential solution: an external device that removes pathogens and toxins from blood. As infected blood passes through the device, it’s mixed with magnetic nanobeads coated with engineered proteins that bind to a range of nasties. Pictured is a protein-coated magnetic bead (blue) binding to Escherichia coli. The bead-bound invaders are then pulled from the flowing blood by a magnet, before the cleansed blood is returned to the patient. When tested in infected rats, the device worked well: the cleansed blood brought down the number of inflammatory proteins and reduced the impact on the rats’ vital organs.
Written by Daniel Cossins
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Image by Donald Ingber and colleaguesWyss Institute at Harvard, USACopyright held by Nature Publishing GroupResearch published in Nature Medicine, September 2014
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bpod-mrc:

14 September 2014

Blood Cleaner

Microbial pathogens in the bloodstream can lead to sepsis, when the immune system goes wild in response to the infection, often causing organ failure and death. It usually takes days to identify the culprit, so doctors use broad-spectrum antibiotics, which are not very effective. Now, though, researchers have debuted a potential solution: an external device that removes pathogens and toxins from blood. As infected blood passes through the device, it’s mixed with magnetic nanobeads coated with engineered proteins that bind to a range of nasties. Pictured is a protein-coated magnetic bead (blue) binding to Escherichia coli. The bead-bound invaders are then pulled from the flowing blood by a magnet, before the cleansed blood is returned to the patient. When tested in infected rats, the device worked well: the cleansed blood brought down the number of inflammatory proteins and reduced the impact on the rats’ vital organs.

Written by Daniel Cossins

Image by Donald Ingber and colleagues
Wyss Institute at Harvard, USA
Copyright held by Nature Publishing Group
Research published in Nature Medicine, September 2014

You can also follow BPoD on Twitter and Facebook

sneakycactus

sneakycactus:

EKGs are going to make me stab my eyes out. I’ve been through Dubin and I feel like “yessss!” when I’m reading it, but then I go look at real EKGs and my brain explodes.

Like half the time there’s a wiggly baseline it’s an artifact and the other half of the time it’s A Fib. And sometimes there’s…

ECG made easy…possibly the best ECG book!